What is Ocular Hypertension Market Report?

Ocular hypertension is defined as elevated intraocular pressure (IOP) without evidence of structural or functional damage by standard clinical tests. The patient with OHT must have open angles and no evidence of an ocular or systemic cause of the elevated IOP. Although genetic influences on IOP are being uncovered, genetic testing does not yet influence the diagnosis of OHT. Many different thresholds have been used to define OHT.

The increase in intraocular pressure (progressive with age, although it may also be due to other disorders or causes) is the main risk factor for developing glaucoma, and therefore, people with ocular hypertension are more likely to suffer the disease. However, the two are different: ocular hypertension means that the intraocular pressure is high, but the optic nerve is not damaged, whereas with glaucoma, the optic nerve has been damaged – and intraocular pressure might be normal or high – which can lead patients to notice a loss of visual field and even central vision in advanced stages of the disorder.

Prior to diagnosis, a thorough examination must be performed to rule out secondary causes of elevated IOP. Additional risk factors must be considered to estimate each patient’s probability of progression to glaucoma. The decision to initiate treatment should be based on the patient’s risk profile, as well as his or her age, medical status, life expectancy, and preferences. Patients need to be followed for changes such as disc hemorrhages, which suggest an increased risk of progression. Both treated and untreated patients should be followed for structural and functional damage suggestive of glaucoma. If these changes are seen, treatment should be initiated or accelerated.

What is Ocular Hypertension Diagnosis & Treatment?

The current mainstays for OHT treatment includes the use of symptomatic medical care to reduce the intraocular eye pressure followed by surgery in high risk individuals who do not demonstrate positive intraocular control with existing medical care. Topical therapies majorly comprise of beta-blockers, carbonic anhydrase inhibitors, prostaglandin derivatives, sympathomimetics, and miotics.

It covers the details of conventional and current medical therapies, and diagnosis available in the Ocular Hypertension market to treat the condition. It also provides the country-wise treatment guidelines and algorithms across the United States.

The DelveInsight Ocular Hypertension market report gives a thorough understanding of Ocular Hypertension symptoms by including disease definition, symptoms, causes, pathophysiology, and diagnosis. It also provides Ocular Hypertension symptoms of treatment algorithms and treatment guidelines for Ocular Hypertension symptoms in the United States.

What is Global Ocular Hypertension Market?

DelveInsight’s ‘Ocular Hypertension – Market Insights, Epidemiology, and Market Forecast—2030’ report delivers an in-depth understanding of the Ocular Hypertension, historical and forecasted epidemiology as well as the market trends in the United States, EU5 (Germany, France, Italy, Spain and the United Kingdom), and Japan.

The Ocular Hypertension market report provides current treatment practices, emerging drugs, market share of the individual therapies, current and forecasted Ocular Hypertension symptoms market size from 2018 to 2030 segmented by seven major markets. The report also covers current Ocular Hypertension symptoms treatment practice/algorithm, market drivers, market barriers, and unmet medical needs to curate the best of the opportunities and assesses the underlying potential of the market

What are the Ocular Hypertension Market Drugs Chapters?

The drug chapter segment of the Ocular Hypertension report encloses the detailed analysis of Ocular Hypertension marketed drugs and late stage (Phase-III and Phase-II) pipeline drugs. It also helps understand the Ocular Hypertension clinical trial details, expressive pharmacological action, agreements and collaborations, approval and patent details, advantages and disadvantages of each included drug, and the latest news and press releases.

Prostaglandin analogs (PGAs) are recommended as the first-choice treatment for POAG because of their efficacy, limited systemic side effects, and once-daily dosing. These drugs reduce IOP by stimulating aqueous humor drainage, primarily through the uveoscleral outflow pathway. Latanoprost, bimatoprost, travoprost, and tafluprost, all PGF2a analogues, are currently approved for glaucoma therapy in the US and EU. Beta blockers, combination therapies, carbonic anhydrase inhibitors constitute second line of therapy for treatment of OHT.

What are the Ocular Hypertension Emerging Drugs?

NCX 470 is a novel, second-generation nitric oxide (NO)-donating prostaglandin analog which is currently being developed by Nicox Ophthalmics in Phase II multicenter, clinical study for the lowering of IOP in patients with OAG or OHT in the US.

What is Reimbursement Scenario in Ocular Hypertension?

While many individuals wait until their claim has been denied before seeking the services of a Social Security attorney, the patient should consider retaining legal representation before submitting the initial application. By working with an attorney or advocate, the patient will ensure that patient’s claim has sufficient supportive medical evidence and that it will be processed through the Compassionate Allowances program. An attorney will do his or her best to make sure that the patient receives Social Security Disability benefits as quickly as possible and will help the patient avoid the lengthy disability appeal process.

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How To Earn Free Ethereum | 4 Easy Ways to Get Paid Today

IDLE EMPIRE
Idle Empire is another good get paid to site which gives many earning methods. Also, is easy to join and is available in most countries. The most common way to earn money here is by taking surveys, offering walls, completing offers, or watching videos.

Go to Withdraw when you decide to take your money out. And of course, Ethereum is one of the methods. The minimum payout threshold is only 1000 coins which is equivalent to $0.10. In some cases, it will require that you complete only one task and be able to withdraw. If you want to learn more about Idle-Empire click here.

PRIME XBT
This is another legit platform where you can take your earnings out. Here you can trade or invest your earnings also. You can easily sign up, just with an email account and can actually create a wallet for free here.

Prime XBT is known for its low fees, it has received multiple international awards for its online trading services, and it has a wide range of markets available. If you are new to tradings, there is an option ‘Copy Trading’ where you can let professionals make the strategies for you. But before doing any move and invest money, you should make your own reach and trade responsibly. If you want to learn more about Prime XBT click here.

FREESKINS
This is a get-paid-to site where you can earn from doing different tasks like surveys, Featured Offers, Offer Walls, downloading APPs, playing games and, more.

To join FreeSkins is really easy, especially if you have a Gmail account, it will take 1 sec. And it is available in almost all countries. When you want to withdraw your earnings go to ‘Shop’ and then choose one of the payout options there.

Ethereum is one of these. The payout threshold is only $2.5 and if you decided to use Coinbase you will need to have only $0.10. It’s one of the easiest sites on the web where you can take your earnings out. If you want to learn more about Freeskins click here.

Summary
Earning Ethereum online using free methods isn’t as hard as most people think. The options listed above are really easy and reliable. So basically you can do some tiny tasks to reach the minimum threshold and get paid immediately.

Also, another last thing I want to mention is that, if you wish to deposit your Ethereum and earn more through interest, a good way is using Binance. Learn more about it by clicking here.

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How Virtual Assistant Service Can Lead to Business proficiency

Availing virtual assistant service for some of your regular and routine tasks will help you to free up a lot of your daily time, which you can eventually utilize into doing something more productive. Virtual assistants from reputed agencies are well trained and can blend into your working environment easily. They can ensure efficiency from day one of their services and prove to be beneficial for your organization.

Whether you are a top-level executive at a conglomerate or you are an entrepreneur struggling to make a space for your start-up in the ever-growing business environment, taking up virtual assistant service will be beneficial for you. You will be able to outsource a lot of your administrative tasks to a virtual personal assistant and expect them to deliver you great efficiency in all that.

Here Is A List of Services That You Can Let Your VA Perform with 100% Efficiency

Calendar Management

This is a significant task that needs meticulous attention. Your VA can manage your daily calendar effectively and ensure that you do not miss any appointments ever. They can also set reminders for you to prepare for meetings in advance, ensuring more efficiency. Availing virtual assistant services from a reputed agency will help you to a great extent as their professionals are trained to handle such work with utmost proficiency and you will not have to spend time training them.

Email Management

You may be receiving hundreds of emails daily and segregating them on the basis of priority may be difficult for you. Here, your virtual PA can make things easy for you by sorting the most relevant ones for your immediate attention, and so on. A shorter turnaround time in email replies will have a great impact on your clients as well as colleagues.

Online Reputation Management

Online reputation has become the most significant aspect of building and maintaining a reputation for businesses or individuals. Availing virtual assistant service from a professional organization will ensure effective online reputation management. Professionals are trained to offer value addition by blending into the working environment seamlessly and ensuring the highest standard of service delivery in building the online reputation.

Lifestyle Services

You can also get assistance in improving your lifestyle by taking up virtual assistant services from a professional firm. Whether it is about paying your utility bills, holiday itinerary setup, or booking a doctor’s appointment, you can get it all done with the help of a VA. Virtual PAs can help you with a lot of regular personal work and let you utilize your time on other tasks that require your undivided attention.

Event Planning

If you have got an upcoming event and have no time to prepare for it, take up an expert virtual assistant service from a reputed firm and you will get 100% efficiency in it. Whether it is about making the list of attendees, researching for the most suitable venue, arranging the best food in town; all can be done by a virtual PA. An expert virtual assistant can handle all kinds of events such as corporate events, client dinners, family parties, regular team parties, etc.

Virtual PA London is one of the top virtual assistant service providers in the country with a 100% client retention rate. Hiring virtual personal assistants from this firm will help you with enhancing your business proficiency to a significant level as you can share a considerable amount of your administrative tasks with the professional and focus more on achieving business growth.

Get in touch with the representatives of Virtual PA London and discuss your task requirements, you will get the best of professionals to finish the assigned tasks with utmost proficiency.

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Home Refinance Stimulus Plan – Based on Present Property Value

There are lots of people suffering from the non-repayment of their home mortgage loan in America and the present government has taken a solid and smart step towards the betterment of the situation. But there are many people who don’t know exactly how to qualify for them and how this home refinance stimulus plan will help them out of this traumatic situation. Here are some tips that would help in realizing the eligibility criteria fixed by the government for this refinance stimulus plan.

If the borrower finds that the value of his house has dropped more than 15% of the real value, then he is eligible to take the advantage of this stimulus plan. This plan has made refinancing of home loan simple, easy and fast so that the homeowners are able to get benefited by the Government’s fixed rate of interest of 2%. Both the President and the Federal Reserve are trying to fix the rate of interest on home loans on 2% and they are working out the solution and the result will be soon in front of the people.

The only condition for applying for home refinance stimulus plan is that the borrower should be living in that house and should have the amount to pay off the remaining debt. This is also very important because to get your loan refinanced you have to pay the outstanding loan amount or get it adjusted into the present principal. It depends upon your lender what option he chooses as you can also negotiate with him for the purpose. The main intention of the plan is to help homeowners save their house from foreclosure and also save some money every month from their present income.

The streamlined refinance option is going to help borrowers get out of this situation spotlessly. This means that even if they had been not able to repay their loan installments since last few months, if they choose home refinance option they will have to pay off the outstanding debt and this will improve their credit score, which will be of great help in future.

Also there are different types of people with dissimilar temperament and thinking. Some would like to get their current loan restructured but some would like to finish off the past and make a new start with the home refinancing loan option. The financial condition also depends here.

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Why Smart Presentations Start With an Office Binding Machine

You put a lot of work into your presentation. You want to make a good impression, but bringing a load of loose papers is going to be risky. And even though the popularity of electronic documents is at at its peak, people still respond positively to holding something in their hands to refer to or make notes on. Hard copies of electronic documents also provide a safe backup plan in case your presentation equipment malfunctions or is not available. With ease you can show everyone that you mean business by coming into your meeting with a professionally bound report. What is the secret? You buy an office binding machine that will keep all the pages of your report together.

There are several different types of binding machines to choose from. It all comes down to what type of binding you are wanting to use. Your choices include wire binding, comb binding, or coil binding. Types of machines exist that can do a combination of these methods. Wire binding can be done in a single spiral or a double loop coil.

Office binding machines can can be purchased for $50 per unit, and the cost increases depending on your office needs. If you will only be needing your machine on certain occasions with small projects, a smaller unit might be appropriate for your needs. However, if you are planning on creating lots of documents on a regular basis, you may find a combination machine to your liking not only because the machine is designed to operate on heavier workloads, but it may also include some time-saving benefits that their smaller counterparts cannot deliver.

When you need to show the world what you are made of, you do not have time to be concerned with losing part of your research. Make an impression at your next big meeting by coming prepared with a professional looking presentation. The right office binding machine will turn your load of loose documents into a bound report that is sure to get their attention.

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Raise the Temperature of Your Presentation With Thermal Binding Covers

It takes a lot of time and effort to put together a really good presentation. And, if you have to create several reports to pass around the meeting, you do not want to avoid losing pages or getting them mixed up. It only takes is one accidental drop to distract your thoughts and cause you embarrassment while you take the time to put them back in order. Those are the times when you might want to add thermal binding covers to your important documents. Not only will this mean all your pages remain together, but it will give your presentation with an extra boost.

Thermal covers provide you the ability to produce bound pages, like a book. There is no hole punching required, and most thermal binding machines come with pre-set heating so you never have to worry about damaging your presentation. These thermal covers come in clear or in a wide array of colors. They also come in several sizes, so you can choose just the right size for your work.

Thermal binding covers work with practically any thermal binding machine. Additional covers and thermal strips can be purchased at your local office supply store or online. They usually run between $3 and $30 per box, depending on number of sheets per box and size of the covers. Putting together the perfect document has never been easier or more affordable.

Do not just hand your associates a pile of papers at the next meeting. Even stapling them together or binding them with a paper clip can send the inappropriate message, especially if it is a client you are trying to win over. Instead, give them a professionally bound report, complete with stylish thermal binding covers. You will make an impression while guaranteeing that all your hard work stays together. What better way to show off all your hard work and prove your worth to the rest of the team?

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Presenting a Real Estate Investment Opportunity to Investors

The first step in raising private equity for any developer is usually to compile a detailed information package. This typically including comprehensive pro forma spreadsheets, investment vehicle structure, site details, and other such information.

However, the packages often neglect to include a snapshot of the deal from the investor point of view. At a high level – how much investment is required, for how long, at what rate of return and how will that investment and return be repaid.

Investors first want to know the basics and establish if a deal matches their investment criteria and how it rates against other deals currently on offer.

If a deal is presented in a beautiful, large package that has to be read from cover to cover to determine its essence it can be a major turnoff to the busy investment professional and casual investor alike.

The more detailed information is really only necessary when an investor has established its suitability on a general level. What is suggested is first producing a more simple deal overview for the potential investor to review.

Begin with the name of the project and a very brief description of the deal (it may be that this is the only document that the investor will look at to determine their interest in your project).

The next piece of information to be included is the cost of the deal and so the equity needed. This part of the document will resemble a traditional debt term-sheet. It shows the investor how much the sponsor is committing to the deal themselves and how much is being sought externally. A typical equity split involves investors providing 90% of the required equity with the sponsor adding the remaining 10% (a 90:10 split).

Moving on to one of the more important sections, for obvious reasons. One needs to display exactly what the investor will receive in return for their equity contribution – “Expected Returns to Investor”. You state what you are going to pay (typically per year) followed by an IRR calculation. The IRR tells the investor what their annual return would be if they invested in your project for x number of years.

The most common time frame for real estate investment opportunities is probably between 3 to 4 years. But, investors can also be sweet to deals that have a high long term return if the figures stack up. When the equity requirement and the associated returns over the timeframe have been established, the next step is proving the model. This requires presenting a breakdown of the various cash flows to the investor and sponsor, along with the refinance assumptions that feed the model.

On the supporting worksheets it is best practice to build the model in such a way that when an investor sees a number in the summary sheet that isn’t clear, they can follow the links and understand its origins.

Constructing an investment summary can be relatively easy, especially if you have the proforma model outlining all the costs and revenues – it is really just highlighting the right information and presenting it in a clear and concise manner.

Without it however, your deal can die before it is even reviewed by the investor.

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Winnie the Pooh – Perfect Present For Children

One of the greatest cartoon characters ever drawn is Winnie the Pooh or more popular as Pooh the Bear. The famous bear has been around for more than eight decades already and has become a part of our lives. Until today, parents and children continue to become patrons of Pooh products that can be found in almost any items. Popular items include bags, shirts, stuff toys, movies, and video games to name a few.

For parents who are planning for special presents for their children, Winnie the Pooh products are very appropriate indeed. Aside from acquiring the huggable bear, Pooh is also represented with a kind heart and a very nice personality all the time. So offering this to children will allow them to recognize the bear as a new best friend. Educational materials such as drawing books and coloring books are also fond items kids will appreciate.

Like any other cartoon characters, Pooh is also present in many parties. Mascots and life size characters are of interest to children so, inviting Pooh mascot in a children’s party is a wonderful idea. Kids will take this as an opportunity to see their favorite bear in real life to play with them. Isn’t fulfilling seeing your kids happy while playing with the bear? It sure it!

Aside from these items, parents can also use other products to keep their children interested with the bear. Giving them cups, mugs, platters, and a set of fork and spoon all printed with Winnie the Pooh logo will definitely grab their attention. Just in case you are still confused on what to give your children, do not forget the power of the Internet. Search for interesting Pooh products online and make sure to find the most appropriate present for your children.

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How to Make Attractive and Effective PowerPoint Presentations

Microsoft PowerPoint has dramatically changed the way in which academic and business presentations are made. This article outlines few tips on making more effective and attractive PowerPoint presentations.

THE TEXT

  • Keep the wording clear and simple. Use active, visual language. Cut unnecessary words – a good rule of thumb is to cut paragraphs down to sentences, sentences into phrases, and phrases into key words.
  • Limit the number of words and lines per slide. Try the Rule of Five – five words per line, five lines per slide. If too much text appears on one slide, use the AutoFit feature to split it between two slides. Click within the placeholder to display the AutoFit Options button (its symbol is two horizontal lines with arrows above and below), then click on the button and choose Split Text Between Two Slides from the submenu.
  • Font size for titles should be at least 36 to 40, while the text body should not be smaller than 24.
  • Use only two font styles per slide – one for the title and the other for the text. Choose two fonts that visually contrast with each other. Garamond Medium Condensed and Impact are good for titles, while Garamond or Tempus Sans can be used for the text body.
  • Embed the fonts in your presentation, if you are not sure whether the fonts used in the presentation are present in the computer that will be used for the presentation. To embed the fonts: (1) On the File menu, click Save As. (2) On the toolbar, click Tools, click Save Options, select the Embed TrueType Fonts check box, and then select Embed characters in use only.
  • Use colors sparingly; two to three at most. You may use one color for all the titles and another for the text body. Be consistent from slide to slide. Choose a font color that contrasts well with the background.
  • Capitalizing the first letter of each word is good for the title of slides and suggests a more formal situation than having just the first letter of the first word capitalized. In bullet point lines, capitalize the first word and no other words unless they normally appear capped. Upper and lower case lettering is more readable than all capital letters. Moreover, current styles indicate that using all capital letters means you are shouting. If you have text that is in the wrong case, select the text, and then click Shift+F3 until it changes to the case style that you like. Clicking Shift+F3 toggles the text case between ALL CAPS, lower case, and Initial Capital styles.
  • Use bold or italic typeface for emphasis. Avoid underlining, it clutters up the presentation.
  • Don’t center bulleted lists or text. It is confusing to read. Left align unless you have a good reason not to.
  • Run “spell check” on your show when finished.

THE BACKGROUND

  • Keep the background consistent. Simple, light textured backgrounds work well. Complicated textures make the content hard to read.
  • If you are planning to use many clips in your slides, select a white background. If the venue of your presentation is not adequately light-proof, select a dark-colored background and use any light color for text.
  • Minimize the use of “bells and whistles” such as sound effects, “flying words” and multiple transitions.
  • Don’t use red in any fonts or backgrounds. It is an emotionally overwhelming color that is difficult to see and read.
  • Many free templates are available for download at http://www.brainybetty.com/MENUPowerPoint.htm and http://www.soniacoleman.com/templates.htm .

THE CLIPS

  • Animations are best used subtly; too much flash and motion can distract and annoy viewers.
  • Do not rely too heavily on those images that were originally loaded on your computer with the rest of Office. You can easily find appropriate clips on any topic through Google Images. While searching for images, do not use long search phrases as is usually done while searching the web – use specific words.
  • When importing pictures, make sure that they are smaller than two megabytes and are in a .jpg format. Larger files can slow down your show.
  • Keep graphs, charts and diagrams simple, if possible.
  • Use bar graphs and pie charts instead of tables of data. The audience can then immediately pick up the relationships.

THE PRESENTATION

  • If you want your presentation to directly open in the slide show view, save it as a slide show file using the following steps.
    1. Open the presentation you want to save as a slide show.
    2. On the File menu, click Save As.
    3. In the Save as type list, click PowerPoint Show. Your slide show file will be saved with a .pps file extension.

    When you double-click on this file, it will automatically start your presentation in slide show view. When you’re done, PowerPoint automatically closes and you return to the desktop. If you want to edit the slide show file, you can always open it from PowerPoint by clicking Open on the File menu.

  • Look at the audience, not at the slides, whenever possible.
  • If using a laser pointer, don’t move it too fast. For example, if circling a number on the slide, do it slowly. Never point the laser at the audience.
  • Black out the screen (use “B” on the keyboard) after the point has been made, to put the focus on you. Press the key again to continue your presentation.
  • You can use the shortcut command [Ctrl]P to access the Pen tool during a slide show. Click with your mouse and drag to use the Pen tool to draw during your slide show. To erase everything you’ve drawn, press the E key. To turn off the Pen tool, press [Esc] once.

MISCELLANEOUS

Master Slide Set-Up:

The “master slide” will allow you to make changes that are reflected on every slide in your presentation. You can change fonts, colors, backgrounds, headers, and footers at the “master slide” level.

  1. First, go to the “View” menu.
  2. Pull down the “Master” menu.
  3. Select the “slide master” menu.

You may now make changes at this level that meet your presentation needs.

Preparing the Handout:

In PowerPoint, choose File | Send To | Microsoft Word. In the Send To Microsoft Word dialog box, choose Outline only to create a text-only document, and click on OK. Minor modifications on this document will give you a handout that can be distributed to the audience.

Create visually appealing slides by adhering to these tips, to ensure that the audience is not distracted from the points you have to make.

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Christmas Gift Wrap Ideas to Make the Perfect Present

Gift wrapping is part of the ritual of giving and receiving that we all treasure. Whether it’s simple Christmas wrapping paper, colored tissue or an elaborate gift bag with all the trimmings, the way you wrap a gift tells the recipient how much you care.

It’s interesting that very small children often value the wrapping as much as the gift. They are excited not just by the act of ripping open the package but also by the box and the paper itself. Many moms will remember having to rescue gift paper from a toddler’s mouth and vainly trying to interest the child in the actual gift.

Many people save Christmas gift wrap and ornaments and recycle them for future use. It’s always a good idea to keep a stock of paper, ribbons and small trinkets handy to ensure that you can produce a present wrapped in a way that reflects your own taste as well as that of the receiver.

It’s so easy to personalize your gift with unusual tags, decorations or colored ribbon. Here are some suggestions:

  1. You can create your own tags very easily by recycling cards that you have received and cutting around the images you like with pinking shears. All you need to do then is make a hole with a hole-puncher and thread pretty ribbon through it to attach it to your gift. This works especially well at Christmas since you can create the tags from the previous year’s cards and make the new season’s card list at the same time. Children love helping with this task — although you need to be sure to give them scissors that are safe for them to use and it may be better if you avoid giving them the hole puncher.
  2. Another recent trend is to add dried flowers, sequins or feathers to your gift. These can be a charming touch especially if you use scented varieties, and you can be sure that they will be treasured and probably passed on to another happy recipient.
  3. Seasonal themes work well with these types of additions, whether it’s spring flowers or fall leaves. You can find a lot of these materials at craft shops for very reasonable prices. Use these stores for inspiration too. One novel idea was to add a range of pretty buttons to the outside of a gift to create a unique look. Of course, you can also add scent yourself by spraying lightly with your favorite perfume.
  4. Some people also enjoy adding wrapped candy or chocolate, either on the outside or in between the layers of paper enclosing their gift. This is reminiscent of the traditional children’s game ‘Pass the Parcel’ in which one layer of paper was removed from the well wrapped gift each time the music stopped. Thoughtful moms made sure that there was at least one small treat inside each layer.

Overall, you want to be sure that the experience of receiving and unwrapping a gift is rewarding in itself, not just because of the item inside. Both the giver and receiver will know how much thought and care has gone into the giving. It may not be just the thought that counts, but thoughtfulness adds an irreplaceable touch and great gift wrapping is a way to showcase that.

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